Roche has appointed Pamela Carroll as its new Global Head of Pathways Biology within in Pharmaceutical Research and Early Development unit.

She will also act as oncology discovery site head at the company’s research facility in Nutley, New Jersey.

Mike Burgess, Global Head Oncology, Discovery and Translational Area, and head, large molecule research at Roche, says Pam “has built a reputation for scientific excellence and leadership in the field”.

She first entered the pharmaceutical industry in 1999 with Bristol-Myers Squibb before joining Merck. Two years ago, she moved to the Belfer Institute of Applied Cancer Sciences at Dana Farber Cancer Institute, Harvard Medical School.

“Her broad knowledge and successful history in leading oncology drug discovery efforts make her is an ideal fit for this position,” Mr Burgess added.

A vibrating gel injected into the vocal tissues of the throat could restore vocal capacity to people whose voices have been damaged by surgery.

The new gel (pictured), developed by Harvard Medical School surgeon Steven Zeitels in partnership with MIT bioscientist Bob Langer, can vibrate up to 200 times per second, mimicking the action of human vocal cords.

Their research has been partly funded by singers Roger Daltrey (of The Who) and Steven Tyler (of Aerosmith), both of whom have suffered loss of singling ability following surgery, thought its main funding source is the Institute of Laryngology and Voice Restoration.

It has recently been reported that Dr Zeitels is helping to treat singer Adele, who has had to cancel her 2011 tour to undergo surgery to alleviate issues with her throat.

Injected directly into the vocal cords, the gel responds to breath and muscle tension by vibrating.

Zeitels is a professor of laryngeal surgery whose patients include singer Julie Andrews as well as Daltrey and Tyler. He was directed to Langer by a number of scientific experts.

Langer is famous for his work on anti-cancer drugs that starve tumours of their blood supply, including Roche’s Avastin, and on time-release drug delivery technologies for chemotherapy.

Creating artificial vocal cords requires a durable material that can bond with the existing tissue and respond correctly to muscle contractions and air movement. Langer has developed a polyethylene glycol gel tailored at the molecular level.

“With synthetic materials, the beauty is you can tailor them and build in the degradation rate or mechanical strength you need because you’re making them from scratch,” Langer commented.

Zeitels and Langer plan to test the gel in a cancer patient for the first time in 2012.

University College Hospital (UCH), London has purchased the UK’s first Biograph mMR hybrid molecular MR system (pictured) from Siemens Healthcare.

In the same month, the hospital’s Institute of Nuclear Medicine brought together clinical scientists to celebrate its 50^th anniversary.

The Biograph mMR – one of the first to be installed in Europe – will be housed in the UCH Macmillan Cancer Centre and used for diagnosis and planning of patient treatment, as well as research.

The world’s first simultaneous whole-body PET-MRI scanner. the Biograph mMR has won the red dot design award 2011 and the Frost & Sullivan Best Practices Award 2011 for its integrated design and scanning capabilities.

At the Institute of Nuclear Medicine’s 50th anniversary, Bruce Rosen, Professor of Radiology, Health Sciences and Technology at Harvard Medical School, gave a lecture on the future of combined PET and MR.

UCH Chairman Richard Murley thanked the UCLH Charity for funding the purchase of the new scanner.

Professor Peter Ell, former Head of the Institute of Nuclear Medicine, summed up half a century of medical imaging, including the first European nuclear medicine brain scanner in the 1970s; the first dedicated mobile renal function apparatus in the 1980s; and the introduction of PET-CT in cancer management.