Merck Pharmaceuticals: innovation through consultation

by Admin 1. May 2006 05:00

 

Merck Pharmaceuticals has again been confirmed as one of the UK’s top employers, following the publication of Pf’s Company Perception, Motivation and Satisfaction Survey for 2005.


THE STUDY, which shows Merck’s standing among UK sales professionals, has risen to 12th position, is the sixth survey in the past two years to commend the company as a leading employer. Last year, Merck secured a top 20 position in the prestigious Guardian-sponsored “Britain’s Top Employers 2005” poll. It was also placed in the top 50 of the FT’s “Best Work Places” lists for 2004 and 2005, and was earmarked at number five as a “rising star” in the Pharmafocus 2006 Careers Survey. These superb accolades are a model of consistency for the West Drayton-based, German pharmaceuticals manufacturer and are the combined result of successful brands, a thriving pipeline and, crucially, a long-term commitment to understanding what is important to its employees.

Loyal workforce

The pharmaceutical industry is accustomed to moderately high levels of staff turnover, particularly in the competitive sales environment. According to the Pf survey, less than five percent of Merck’s field force is seeking to find employment within alternative pharmaceutical companies in the next year. This is a vastly superior to the industry average of 16% and reflects the efforts Merck has made to engage with its staff to develop and improve its performance.
That so many of Merck’s workforce are keen to stay put should come as no great surprise. Merck compares favourably with the rest of the industry, performing ahead of the industry average in 12 of the 16 satisfaction factors surveyed in the Pf study. Furthermore, Merck has also performed well against fellow Small-to-Medium Enterprises (SMEs) – companies whose revenues sit somewhere between £20 million and £100 million. Merck outperformed a large sample of the best-known SMEs in all but three satisfaction categories.
 
Jim Golby, HR Manager, believes the latest figures underline the company’s efforts to work in partnership with its employees and respond to their needs. “We have invested heavily in seeking to establish what’s important to our field force. Not only have we conducted several internal and external studies within this area, significantly, we have acted upon the findings. All too often, employers fail to listen. We have kept asking, kept listening and, most crucially of all, we have done something about it. The loyalty of our sales professionals proves that we are now reaping the rewards. Our teams have returned some outstanding performances and are renowned for going the extra mile with customers. That only happens when a team is truly motivated, feels appreciated and wants to make a difference.”

Record revenues

The survey results represent just one aspect of a highly successful year for Merck. The company eclipsed its record sales revenues in 2005, both in the UK and globally – making it the most successful year in Merck’s 337 year history. This is no mean feat, as revenues in 2004 had themselves beaten all previous records. Global group revenues in 2005 were 5.9 billion. Growth was driven by the sustained success of Glucophage-SR, which has been acclaimed as the most successful launch for Type-II diabetes in the UK. David Garmon-Jones, Head of Pharma Sales, said: “UK sales grew by an impressive 17% in 2005, buoyed by successful product launches and the continued success of  established high profile brands. The pharma sales force has really enjoyed launching Glucophage SR. It’s an excellent, innovative product which delivers real tangible benefits for our customers and, most importantly, patients.”

Merck was also boosted by the success of Erbitux metastatic colorectal cancer. The product was the first drug to emerge from Merck’s oncology pipeline when it gained approval for launch in the UK in 2004. It recently received marketing authorisation for the treatment of head and neck cancer by the EMEA. Denise Richard, Head of the Oncology Business Unit, said: “2006 looks like being yet another exciting year for Merck Oncology with our launching of the new head and neck cancer indication for Erbitux, our ground breaking mono-clonal antibody product. We will also launch Uftoral, another new addition to the Merck Oncology portfolio.”

In fact, Merck’s current portfolio is strong, comprising drugs for diabetes, cancer, cardiovascular diseases - in particular hypertension, lipid management and angina – and gastroenterology. Neil Dugdale, Head of the Gastroenterology Business Unit, commented: “Our Gastro sales team continues to go from strength to strength. 2006 looks like being another superb year for our highly professional sales team.”

Merck’s pipeline is also healthy, with compounds in late-stage clinical development in the areas of cardiometabolic, oncology and neurology.

Company culture

The Pf survey earmarked “Company Culture” as a key aspect of importance for sales professionals across the industry. Survey respondents from Merck, totalling almost half of the company’s UK field force, commended the organisation’s culture. In fact, satisfaction ratings for the ‘Company Culture’ at Merck were, impressively, almost double the industry average. Now that really tells you something!

Merck’s philosophy is clear from the outset of any placement within the company. Trainee reps, for example, receive more than 30 days of dedicated training within their first year. John McIlree, Head of HR, Training and Development, explains how the development of employees lies at the heart of the company’s culture: “Merck is committed to life-long learning and provides many ongoing initiatives that develop employee potential, both for current roles and further opportunities,” he says. “A career with Merck means an investment in your future development.”

The company encourages its employees to innovate across all areas of the business. Clearly the satisfaction of its field force is testament to a long-term innovation programme aimed at understanding its employees and delivering measures that improve performance.

Merck KGaA aims to be number one in its core businesses through, it says, “innovations created by talented and entrepreneurial employees.” So are you an innovator? Have you the skills necessary to thrive in a growing company that consistently satisfies its field force and remains committed to its development? If so, there’s a company in West Drayton that would be delighted to hear from you. It’s nice Merck, if you can get it.

Who are Merck Pharmaceuticals?

Merck Pharmaceuticals is a division of the oldest pharmaceutical and chemical company in the world

• Its parent, Merck KGaA, was founded in 1668 and employs over 29,000 people globally
• Merck Group sales grew 9.9% to 5.9 billion in 2005
• 68% of ethical sales in 2005 were in Europe, with double-digit growth in the UK led by sales growth of products such as Glucophage SR and Erbitux
• Merck’s innovation stretches outside pharma - it is the world’s largest supplier of liquid crystals
• Around 80% of LCDs in TVs, PCs, mobile phones etc., contain Merck liquid crystals
 
 
For enquiries regarding future opportunities, please contact jgolby@merckpharma.co.uk
 
 
For more information visit www.merckpharma.co.uk and/or www.merck.de

Tags:

Features

Career Insights with comments from Lucy Randle, STAR Medical

by Admin 1. May 2006 05:00
Joanne Barnes, winner at this year’s Pf Awards, has worked as a Clinical Nurse Advisor for four years. She told Pf why she loves her job with AstraZeneca, and why she thinks enthusiasm for what you do is so important.
What do you enjoy most about your job?

Probably the variety. I cover two different disease areas, so I get to meet lots of different people. I also enjoy the autonomy I get in this role, and also the unpredictability, as I never know who I am going to meet. I feel I have been lucky to find a job I actually like.

What do you find challenging?

It’s probably the same with all jobs, but I find it frustrating how long things take, so even when a decision has been made it takes a long time for it to be put into action. It is also difficult when people have a lack of enthusiasm for a disease area. GPs have differing agendas and don’t always share your enthusiasm for a disease area.

How did it feel to win at the Pf Awards?

It was quite amazing. I was totally caught off guard but thrilled to bits. The fact that I won really is a reflection on my team who supported me, and my manager who was a great source of encouragement.

What do you think it was that made you stand out from the crowd at the assessment day?

After I had got through the screening, I was determined to go into the assessment day just doing my job and not trying to make it something that it wasn’t. I think it may have been that honesty that made the difference, as well as my belief in myself and what I’m good at. I think if you are enthusiastic about something you will be good at it.

What advice would you give to someone hoping to excel in a similar role?

Once again, I would say ‘Be enthusiastic’ – if you don’t enjoy what you do you will never succeed at it. In this role you are constantly caught in between the NHS and the pharmaceutical industry, so you’ve got to be able to think outside the box. You need to put in the work, as nothing is going to come to you without it. Finally, I would emphasise that it is important to know your limitations and be prepared to ask for support when you need it.

Lucy Randle of STAR Medical provides some insight into the role of Nurse Advisors within the industry and gives guidance to those nurses thinking of a career change into the Pharmaceutical industry.

A change of career

For some nurses, the NHS is becoming an increasingly inhospitable place to work – sorely affected by a lack of resources and training opportunities, many sympathise with the popular expression ‘overworked and underpaid’. Though some nurses may feel compromised by the prospect of working in a more commercial environment, others relish the challenge.

The role

As a Nurse Advisor you will be an independent advisor, ‘sponsored’ by a pharmaceutical company. You will remain patient-focused and work in an ethical, non-promotional manner to assess, review and audit hospitals and GP practices. When it is of real benefit, you will switch a patient to your company’s product. You may also work closely with PCTs and Health Authorities to develop policies and guidelines.

Experience and qualities

You will already be a Registered Nurse, ideally ENB 998 qualified and a member of the NMC, and you may have the opportunity to become ABPI qualified. Ideally your experience will be in a specialist therapy area, for example diabetes, asthma/COPD or CHD, and you will have gained a qualification in this. You will also be able to demonstrate commercial awareness – you may already have some sales experience, for example. Essentially, you are an excellent communicator, results-driven and self-motivated. You are happy to work autonomously, but also as part of a team.

Good for practices

You will be a valuable resource for many busy GP practices. While the practice members are able to go about their usual business, you can spend time reviewing procedures and implementing best practice. This can result in a significant improvement in patient treatment for the therapy area you are focusing on. You may also spend time educating staff and patients alike about how best to use your product.

Good for pharmaceutical companies

Nurse Advisors work to ensure that their sponsoring pharmaceutical company becomes a leader in the therapy area of focus by setting new standards and innovating.

Good for you

You will be welcomed into practices and make a valuable contribution to staff training and patient health. Your employer will reward you with training, incentives, opportunity for career progression and an attractive salary package in comparison to the NHS.

If you are interested in a change of career, please contact us for access to a broad range of challenging Nurse Advisor roles.

Sponsored by STAR Medical

Tags:

Features

FROM THE FIELD

by Admin 1. May 2006 05:00

 

Conferences

Tim, our representative speaking ‘from the field’, gives his light-hearted angle on the day-to-day issues faced by medical sales professionals.

MOST OF YOU will have been to some sort of company conference this year. It probably involved a few nights sleeping in a box with a bed and a TV in it, in either a hotel near an airport in this country or a hotel abroad ludicrously far from one.

I apologise in advance, but I am about to debunk a popular myth. Going abroad for a conference is not fun, and that’s an end to it. It requires a day travelling there and a day travelling back that could be spent doing something far more productive and enjoyable, like admin or watching paint dry. You see nothing of the country you visit except for one free afternoon, which is usually spent in the local bars, and an organised evening in a restaurant away from the hotel. So much time is spent indoors that it is not until you get home that you remember how great daylight is.

Please don’t think of me as the Grinch who stole conference. I love these annual gettogethers. Each one reduces the cost per event ratio of my dinner suit. And I don’t have to cook or buy food and drink for a few days. Or make the bed.

And it’s not all about saving money and laziness. It is also a chance to meet up with friends made on training courses or at other meetings, a chance to network and make new friends, a chance to let someone else look after the kids and, for some, a chance to wear fancy dress to work.

Medical reps need self-confidence, but to go to a conference dressed as Elvis, a hula girl or a member of the opposite sex in front of your work colleagues shows a lack of inhibition that would make the Village People blush. But we need these delegates: they add a bit of colour to the drab hotel interior. I appreciate their presence immensely. I do, however, refrain from joining in myself. My feelings on this are the same as on many other things in life: I love to watch, just don’t make me do it.

But to go back to my previous point, and I am sorry to bang on about this, everything that makes a conference good can be done in the UK. So I appeal to my conference organisers: give us reps a treat this year – send us to Heathrow. Unless you were thinking of Japan. I’ve always wanted to go there.

Tags:

Features

Innovation, communication, reputation: watchwords for success in 2006

by Admin 1. May 2006 05:00

 

The ABPI’s annual report for 2005 shows an industry high on innovation but low on reputation. Clearly the traditional representative has a major role to play in improving public health.

 

 

“We must dispel a strange national characteristic – discovering many innovative medicines but keeping them from our own patients.”

Dr Richard Barker, Director General, ABPI

 

 

THE UK must “dispel a strange national characteristic – discovering innovative medicines, but keeping them from our own patients,” an ABPI report has warned.

The UK remains bottom of the European league in terms of spending per head on medicines, while the percentage of the NHS budget spent on medicines has dropped to 11%.

In response, the ABPI has urged the sector to pursue its goal of bringing new medicines to patients with “pride and determination”.

Stormy weather

According to Partners in Healthcare, the ABPI’s annual review for 2005, the annual cost of British prescriptions averages just £205 per patient – one of the lowest in Europe. Figures also show that the prices of medicines are over 21% lower in real teams than they were 10 years ago, while the balance of trade in pharmaceuticals – last year the highest of any sector in British industry – dropped by 8% last year.

Dr Richard Barker, Director General of the ABPI, warned that the public and politicians needed to recognise the value for money the NHS was getting for its investment in UK medicines. “Our latest statistics show that there are some worrying signs over the health of the pharmaceutical industry in the UK,” he said. “We have serious concerns over the research and manufacturing base in the country, and our balance of trade – while still the envy of many other industries – is now showing a decrease.”

Looking forward, the report warned of “choppy political waters” ahead as pressure on the NHS budget increased. It notes that the industry needs to develop more evidence to support its conviction that by keeping patients out of hospital, medicines are part of the solution to NHS funding and not part of the problem. Moreover, Dr Barker highlighted the need for more British patients to benefit from advanced therapies developed in the UK. “We must dispel a strange national characteristic – discovering many innovative medicines but keeping them from our own patients,” he said.

The report highlights access to medicines and informed patients as dominant themes for all stakeholders in the NHS in 2006. These issues, it,says, underline the value of innovation in the UK sector.

“Quite rightly, patients have been demanding access to potentially life-saving and life-enhancing medicines. They have even taken their demands to the High Court,” says Vincent Lawton, President, ABPI. “But beyond the issues of access to medicines, this issue has also raised two positive themes: it speaks volumes about the value of medicines and the cutting edge research work that the industry does, and it is a salutary reminder of the value and importance of involved, and informed, patients.”

Putting the message across

The industry’s reputation remains a major focus for the ABPI – yet, while independent research shows that the majority of the public have a positive view of the pharmaceutical industry, critics repeatedly question its integrity and trustworthiness. To this end, Dr Barker urges the sector to demonstrate its value through communication and innovation. “We must engage in media discussion openly and robustly, and we must pursue our goal of bringing new medicines to patients with pride and determination,” he said.

The issue of communication is central to the role of the medical representative, who remains a significant weapon in the armoury of drug companies to deliver information to the medical profession. In its analysis of 2005, the ABPI was critical of aspects of the House of Commons Health Select Committee Report – some proposals from which, it said, risked “artificially limiting” the ability of doctors to receive information about medicines.

The ABPI Review cited three claims from the HSC report which, it said, were “fundamental misconceptions” whose inaccuracy called into question measures intended to restrict doctors’ freedom to prescribe and companies’ ability to provide information to the medical profession.

 

“Modern and innovative medicines are part of the solution to the NHS’s funding situation, and not part of the problem.”

Vincent Lawton, President ABPI

It countered HSC claims that the UK’s consumption of drugs is “vast and increasing” by pointing out that the UK remains bottom of the European league in spending per head on medicines. Moreover, it dismissed suggestions that the months following a product launch were followed by a “prescribing explosion”. According to the ABPI, the UK has one of the lowest usage rates of new medicines during their first five years on the market.

Finally, the HSC report suggested that intensive marketing encouraged “inappropriate prescribing”. In support of the role of the traditional representative, the ABPI responded by saying that while most doctors receive only a handful of representative visits a month, the majority say they value the clinical and product information provided.

In a rigorous defence of the value of industry practice, the ABPI warned: “Artificially limiting the ability of doctors to receive information about medicines and restricting further their ability to prescribe medicines already licensed for use – as proposed in the report – would be a step backwards in the National Health Service’s bid to prevent disease and increase access to the best quality treatment.”

Moving on up

The ABPI was, however, pleased to see that the HSC report acknowledged the importance of the UK pharmaceutical industry in the development of new medicines, noting that its discoveries “have improved many people’s quality of life, reduced the need for surgical intervention and the length of time spent in hospital and saved many lives.”

Despite this, Vincent Lawton urged the Government to ensure the UK remains an attractive market for pharmaceutical R&D. “If we wish to preserve the benefits brought by one of the country’s most successful industries, it is

vital that the Government ensures an attractive return for successful innovation, with its significant cost in terms of R&D, when deciding how much they are willing to pay for medicines,” he said.

“In a competitive global industry, the UK must remain an attractive and viable place for pharmaceutical companies to invest. With around 40% of new medicines introduced in the past ten years supporting the Department of Health’s priority areas of cancer, coronary heart disease, mental health and diseases of the elderly, the pharmaceutical industry is making a major contribution to improving the health of the nation and the productivity of the NHS.”

The ABPI’s Annual Review 2005: Partners in Healthcare can be viewed at the ABPI website, www.abpi.org.uk

Tags:

Features

Pf poll measures reality

by Admin 1. May 2006 05:00
The eagerly-awaited results of the premier poll of the UK medical sales market, where sales professionals become the judges, have arrived. Pf’s fifth Company Perception, Motivation and Satisfaction Survey has been conducted independently by the Royal Statistical Society – and as always, the results make essential viewing. We take a close look at the top performers of 2005. Has your company got the Rx factor? 

The Company Perception, Motivation and Satisfaction Survey is one of the most significant pieces of research in the UK medical sales industry. Constructed by the Royal Statistical Society at the Nottingham Trent University, the survey provides a benchmark of field force remuneration, motivation, satisfaction and recruitment.

This year there were 1,507 respondents to the survey – marginally higher than the previous study in 2004. Yet again, the results provide a stimulating insight into the industry, the general feeling in the field, and what motivates medical representatives. The survey also highlights readers’ Employers of Choice, offering a fascinating glimpse of how pharmaceutical companies are perceived externally. The five-year history of the survey provides a useful benchmark for the progress the industry is making.

The following analysis of the 2005 survey looks at five specific categories – the Rx factors. The final judgements are here.

1. ‘Across the Universe’

The profile of survey respondents was broad, underlining the diversity of individuals who pursue careers in medical sales.

Rx Factor judgement:
The 2005 sample bore a striking resemblance to the previous survey in terms of size and the most frequently represented age group. The latter statistic has remained constant throughout the survey’s five-year history. However, it is worth noting that the 35-44 age band was only one percentage point lower than the most common band (25–34), and that 58% of the sample were over the age of 35. This is reflected in the sample’s experience, with over half of the respondents having worked for over 8 years in the medical sales industry – a clear increase from 2004.

2. ‘You’re the One That I Want’

Respondents were asked to score pharmaceutical companies according to their perception of them and how desirable they were to work for (1 = very low, 3 = no comment, 5 = very high). As always, respondents were not permitted to nominate their own company. The final results represent a balance between positive and negative perceptions.

Rx Factor judgement:
Roche has emerged as the Employer of Choice for 2005, toppling Eli Lilly, who had topped the chart in the previous two years. Boehringer Ingelheim retained second spot, while Schering-Plough, Janssen-Cilag, Schering Healthcare, Procter & Gamble and Novartis all returned consistent performances. GSK made a welcome return to the top 10 after a year away, but there was still no place for two of the sector’s big guns, Pfizer and AstraZeneca. In fact, the remarkable advances in the perceptions of small-to-medium sized pharma companies continued in 2005, with the top 20 including a growing number of smaller companies. Pf will examine this trend later this year.

 

This experience is matched by results, with 70% of respondents claiming to have either ‘above average’ sales results or being among the highest sales in their company. The sample, therefore, is of a higher than average quality – which is reflected in the remuneration analysis later in the article.

3. ‘Satisfaction’

Respondents were asked to indicate which aspects of their working environment were important to them, and how satisfied they were with a range of fifteen motivational factors. The four major employment categories revealed the following results:

Rx Factor judgement:

Clearly, sales professionals remain motivated by their salary. Interestingly, they appear less motivated by other elements of a remuneration package such as bonuses, car policy, pensions and share schemes. Equally, respondents find that good working relationships with their direct managers are important; while for front line sales professionals, belief in their products is essential.

In fact, all four major employment categories demonstrated belief in their current products. The industry also seems to be satisfying its sales representatives with regard to pensions, which were a high-profile news topic across all industries throughout 2005. The previous Pf survey hinted at a degree of anxiety over the state of product pipelines. However, it would appear that confidence in R&D has returned, with future product pipelines picked as a leading source of satisfaction across all categories.

4. ‘Money, Money, Money’

The issue of remuneration, and specifically salary, commonly earns the most attention when survey results are published. Clearly, pay structures differ from company to company and are based on a number of complex factors. The Company Perception, Motivation and Satisfaction Survey gathers and analyses remuneration data in a variety of ways. For the purpose of this article, Pf has focused on the median figure for salaries, where ‘median’ is the value in the middle when all values are put in order from smallest to largest. The median figure is different from the average (mean) figure.

It is important to recognise that pharma companies traditionally consider the length of service and quality of results when calculating salary. The following median results need to be assessed in the context of what is a highperforming and experienced survey respondent profile. With over half of the sample (51%) having over 8 years’ experience in medical sales, and 70% of it comprising above average performers and highest achievers, it is only to be expected that the figures for median salaries and bonus payments would be high.

The message for sales professionals who believe they are underpaid, therefore, is to persevere and focus on further improving results – and the rewards will follow.

Rx Factor judgement:

According to the survey, 60% of respondents across all categories consider that their remuneration package is appropriate for the job they do. This continues what appears to be a maturing trend within the sector with regard to how sales professionals are rewarded for their endeavour. In 2003, over half of the market believed they were underpaid. By 2005, two-thirds appear content with their remuneration packages. While we would all argue for more money, this shift in perception is clearly good news for pharmaceutical companies.

5. ‘Should I Stay or Should I Go?’

Finally, the survey revealed an increase in the number of respondents looking to move companies. While over half of the sample (56%) indicated that they were happy to remain in their current positions, 16% are considering moving companies – which is up from 13% in 2004. Moreover, a further 23% would consider moving position within the same company.

Final judgement:

For the second year running, the majority of sales professionals appear to be happy with their products, their management and, crucially, their salaries. However, an increased number of respondents are looking for their next move – but the lure of big pharma is no longer as powerful as before.

Voting lines for the Rx Factor have now closed. But, as ever, the competition continues.

Tags:

Features

Europe outgrows North America but price cuts hit UK

by Admin 1. May 2006 05:00

 

With steady growth in major markets, flourishing sales in developing countries and more than 2,000 products in clinical development, the future for global pharma looks bright. Pf examines global sales in 2005.

THE EUROPEAN pharmaceutical market outgrew its North American counterpart last year, audited sales figures for 2005 reveal.

Global sales rose 7% to $602 billion, with Europe accounting for a 7.1% increase ahead of Japan (6.8%) and North America (5.2%). However, for the first time, the UK market experienced negative growth (–2.2%).

The annual figures from IMS Health show that the most dramatic growth occurred in emerging markets such as China, Mexico and Russia, signalling an important shift in industry attention towards developing markets.

Price cuts hit UK

The decline in the UK was driven by PPRS price cuts and Category M price cuts on generics. Of the top five therapy classes (see Figure 1), only nonnarcotic analgesics grew in 2005. Sales of cholesterol regulators dropped by 20%, due as much to the fall in the generic simvastatin price as to PPRS cuts. In 2004, calcium antagonists made up the fourth-ranked therapy area by sales and ACE inhibitors ranked sixth. Both have now dropped down due to patent expiries. Equally, NSAIDs have fallen away from their previous position of eighth as a result of the Cox II scares and withdrawals.

The negative growth in the UK market for 2005 follows increases of 8% in 2004 and 11.3% in 2003. During the same three-year period, growth in secondary care outstripped that in primary care; the 2005 IMS hospital audit recorded growth of 2.2%, while primary care fell back (–3.5%). Figure 2 shows the leading UK products in each sector.

The global pattern

The ten major markets, which account for 81% of the total global pharmaceutical market, achieved a growth of just 5.7% in 2005 compared to 7.2% the previous year (see Figure 3). However, developing markets such as China, Korea, Mexico, Russia and Turkey outpaced global performance, all experiencing double-digit growth.

“As growth in mature markets moderates, industry attention is shifting to smaller, developing markets that are performing exceptionally well,” said Murray Aitken, IMS Senior Vice President, Corporate Strategy. “Many of these countries are experiencing significant GDP growth – which helps finance improvements in their healthcare systems, increases patient access, and fuels the double-digit growth we are seeing. Pharmaceutical manufacturers are working to address the unmet healthcare needs in these markets as a means to improve overall business performance.”

China, in particular, achieved an impressive growth of 20.4%, with total sales of $11.7 billion; this represents the third consecutive year in which it has achieved growth above 20%. IMS Health has predicted that China will be the world’s seventh largest pharmaceutical market by 2009.

Ray Hill, General Manager of IMS Global Consulting, commented: “The combination of a healthy economy and increasing diagnosis and treatment rates makes China extremely attractive to multinational pharmaceutical companies. Many of them are expanding their presence in China now because they recognise the significant long-term business opportunities that market presents.”

A year of innovation

So what stimulated worldwide growth? While the increasing longevity of the population, rising wealth and new applications for existing products all contributed to growth in 2005, the introduction of innovative new treatments had the greatest impact. (See Figure 4.) Last year, 40% of total market growth was fuelled by the introduction of new products, including 30 new molecular entities launched in key markets.

Notable product launches in 2005 included Byetta®, the first in a new class of medicines for improved blood sugar control in patients with Type 2 diabetes; Lunesta®, which treats insomnia, decreases sleep latency and improves sleep maintenance; and Macugen®, which treats neovascular age-related macular degeneration.

“We have seen some exceptional advances in the treatment of critical disease conditions, with many promising therapies now in Phase III clinical trials, encompassing both vaccines to prevent disease and more effective life-saving therapies,” said Murray Aitken. “For example, Gardasil® and Cervarix® promise to be effective vaccines against HPV, the cause of nearly three-quarters of the cases of cervical cancer which last year contributed to the death of more than a quarter of a million people worldwide. These and other therapies for the treatment of cancer, cardiovascular disease and diabetes will improve life expectancy and enhance patient quality of life.”

Prospects for the future are encouraging. In 2005, more than 2,300 products were in clinical development, up 9% from the 2004 level and up 31% over the past three years. A promising range of drugs are now in Phase III clinical trials or preapproval stage, including 96 oncology products, 51 products for treating cardiovascular disease, 37 for viral infections and HIV, and 28 for arthritis/pain.

2005 was also the year for blockbusters, with the number of products with sales exceeding the billion-dollar level reaching 94 (compared with only 36 in 2000) including 17 new members. While six blockbusters are expected to lose their patents in 2006, the launch of new products and the continued growth of those already on the market will result in an increasing number of blockbusters over the next five years.

A bright future for pharma?

For many pharmaceutical manufacturers, 2005 was a year of transition as they responded to cost containment challenges, regulatory setbacks and safety issues. IMS Health predicts further changes ahead. Generics, it says, will assume a more central role as patients bear a greater percentage of their own healthcare costs and payers seek to restrict the growth of healthcare expenditures, and price moderation for brands is likely as a result.

“Moderating growth in the top ten markets, along with the focus on generics as a cost-effective alternative to branded drugs, will present challenges to the pharmaceutical industry worldwide,” said Murray Aitken. “But we don’t expect these to stand in the way of pharmaceutical growth. What is critical to long-term success in the marketplace, however, is the need for payers and manufacturers to jointly strike a balance between prevention, treatment and cost containment. This is an urgent imperative with new delivery systems on the horizon to improve patient quality of life and vaccines to prevent disease.”

Despite these challenges, however, the same factors that boosted growth in 2005 will continue to play a part. It will be a combination of surging demand driven by ageing populations and successful innovation in areas of unmet need that continues to fuel the growth of the industry.

Data in this article has been kindly provided by IMS Health. Additional information is available at 

www.imshealth.com

Tags:

Features | Features

Pride unprejudiced mending the public image of pharma

by Admin 1. May 2006 05:00

 

Pf spoke to NICE’s Professor Sir Michael Rawlins, who explained how this year’s Prix Galien Awards provide an opportunity for the pharmaceutical sector to be proud of its achievements as innovators.

THE NORTHWICK PARK tragedy has further damaged the pharma industry’s already flawed public reputation. Admitting to a career in the sector is often done more in apology these days than in pride. Pharma no longer appears to be a blue-chip profession. And yet a career in pharmaceuticals is one aligned with innovation, value and public benefit.

When the next winners of the prestigious Prix Galien Awards are unveiled at a lavish ceremony at the Houses of Parliament this September, the victors will have earned the respect and acclaim of the toughest of judging panels. The panel, which comprises leading health technology appraisal experts from across the NHS, is chaired by the most eminent judge of them all: Professor Sir Michael Rawlins, Chairman of NICE. To win the prize, the participants really have to earn it. The fierce nature of the competition underlines the true value of the pharmaceutical industry and how a career within the sector makes an important contribution to public health.

Professor Sir Michael Rawlins has chaired the Prix Galien judging panel for nine years. His passion for new therapies and what they can do for the nation’s health was stimulated much earlier in his career, when he was a clinical pharmacologist. The Prix Galien, he feels, plays an important role in the pharmaceutical industry in that it recognises and rewards innovation that would otherwise often go unnoticed:

“The Prix Galien recognises the technical, scientific and clinical research skills necessary to discover and develop innovative new medicines. I am proud to chair the panel because it provides me with an opportunity to acclaim, publicly, the contributions made by basic and clinical scientists within the pharmaceutical industry.”


What is the Prix Galien?

The Prix Galien is an internationally recognised award within the pharmaceutical industry. Launched in France in 1969, it was named after the Roman philosopher Claudius Gelenus (AD 131–201) – widely regarded as the ‘father of modern pharmacology’ – and rewards outstanding achievement in research and development.

The UK Prix Galien was established 15 years ago to recognise the UK industry’s achievements in the evolution of medicines. Its main purpose is to recognise and reward innovation. Winners of the UK Prix Galien are entered into the International Prix Galien, which runs every two years and pits medical innovators from across the globe against each other. 


Contributing to patient welfare

Innovation, says Professor Sir Michael, is at the heart of the pharmaceutical industry. “When innovation is achieved, it meets unmet clinical need.” As such, the Prix Galien judges look not only for the highest quality of discovery and development, but also for therapies that make the greatest contribution to patient welfare.

Previous Prix Galien winners include high-profile drugs such as Herceptin (2002) and Viagra (2000) – the former significantly improving survival times in patients with aggressive breast cancer, the latter bringing the whole issue of men’s health, particularly impotence, into the public eye. Likewise, Meningitec (2000) brought about a 75% drop in cases of meningitis C in young babies and children, while Glivec (2002) provided the only treatment option for gastrointestinal stromal tumours. (See ‘Prix Galien past winners’ below.)

The Awards are held every two years, with the UK winners being put forward for the International Prix Galien. Last time out, in 2004, the Prix Galien medal was jointly awarded: Roche’s Fuzeon and Wyeth’s Prevenar shared the top prize ahead of a strong list of contenders from across the UK industry. Advate (Baxter Healthcare), Crestor (AstraZeneca), Lantus (Aventis), Neulasta (Amgen), Tracleer (Actelion Pharmaceuticals), Velcade (Ortho Biotec), Vfend (Pfizer) and Xigris (Lilly UK) completed the shortlist. “The judges were impressed by the quality of all the shortlisted applications; but overall, Fuzeon and Prevenar were considered to be of special worth for the award of the Prix Galien,” says Professor Sir Michael.

For the participating companies, the result is significant. “The Prix Galien Award represents the output of a rigorous review by a prestigious panel that ultimately recognises and rewards true innovation within the industry,” says Simon Harris, Business Unit Director for Specialist Products at Roche. “Upon winning the Prix Galien we had a broad internal communication programme to highlight the success of Fuzeon in gaining this award. Our employees certainly recognised that they were working for a truly innovative pharmaceutical company that ultimately made a significant impact on patients’ lives.”

 
“The industry seems to be struggling along the bottom of the curve as regards its reputation at the moment. The Prix Galien can be used to demonstrate to a wider public audience the achievements of the pharmaceutical industry.”
– David Gibbons, Corporate Affairs Project Manager, Wyeth

Winning innovations

The public impact of medical innovation is unparalleled. It’s also largely unsung. A glance at the profiles of the 2004 Award winners provides unequivocal evidence of the value of pharmaceuticals.

Prevenar is a conjugate vaccine offering protection against seven serotypes of pneumococcal infection. These account for 80% of invasive pneumococcal disease in infants and young children. Trials involving over 37,000 children suggested that 1,000 cases of pneumococcal meningitis, septicaemia and pneumonia, around 27 of them fatal, would be prevented each year in the UK. “The panel was impressed by the potential impact that this product will have in preventing serious infection in young children and infants,” says Professor Sir Michael.

Fuzeon is the first of a new class of anti-retroviral drugs known as fusion inhibitors. It represents a new way of tackling the HIV virus: preventing it from entering the cell, rather than acting inside the cell (as other HIV therapies do). It thus offers new hope to those patients who have become resistant to other therapies.

Fuzeon’s victory in 2004 was due not only to the obvious health benefits of the therapy, but also to the sophistication of its manufacturing process. “We were impressed not only with the results of the clinical trials of the product,” says Professor Sir Michael, “but also the extraordinarily complex manufacturing issues that had to be solved.”


“Fuzeon has given me the chance to look towards the future and have some dreams.” – an HIV patient

To win the Innovative Product Award, a drug must be judged to represent a genuine breakthrough in its therapeutic area and to demonstrate innovation and therapeutic advantages over other treatments already in existence. Furthermore, it must have demonstrated a significant therapeutic effect on patient health.

In the case of Fuzeon, the first patient to be given the HIV treatment attended the 2004 ceremony and praised the drug for giving him the chance to “look towards the future and have some dreams”.

Patients are a virtue

The patient is playing an increasingly significant role in the delivery of healthcare – a fact that Professor Sir Michael is happy to acknowledge. “Patients have several roles,” he says. “Most importantly, of course, they play an essential part in the clinical research as participants and subjects. But they also have other roles: they can (or at least should) contribute to specifying the desirable characteristics of a drug delivery programme; they should be intimately involved in the development of quality of life measures; and they should – to a much greater extent than in the past – be involved in making decisions about the trade-off between benefit and risk.”

The growing role of the patient in the development of medicines in the UK is influenced heavily by the relationship between the pharmaceutical industry and the general public. Current public attitudes towards the industry are disappointing. Despite the fact that the industry ploughs around 20% of its turnover back into R&D, its reputation remains at a low ebb. The Prix Galien can help to rectify this by enabling the industry to focus on its strengths and highlight its almost forgotten status as one of the UK’s most innovative sectors.

Professor Sir Michael Rawlins believes that the Prix Galien can improve the wider public perception of the pharmaceutical industry. “I hope it brings to the public’s attention the contributions of individuals, and teams, working in the pharmaceutical industry. What they do is often forgotten and should be made more public.”

Clearly, a career in pharmaceuticals is a worthwhile one. It is, in fact, one of the few industries that can make a genuine difference to society. Be proud of it.

This year’s Prix Galien Awards will be held on 26th September at the Houses of Parliament. For further information visit www.westawaygillis.co.uk

Tags:

Features

Interested in a career in recruitment?

by Admin 1. May 2006 05:00

 

Many of you will have dealt with recruitment agencies during your career but have you stopped to think what life is like in the recruitment industry? We’re delighted to be able to take you behind the scenes at IHS to find out more.

The team behind IHS’ continued growth and success

At IHS we are very proud of the first class reputation and position as a market leader we’ve achieved since 2001. Such reputations are not established without a great deal of hard work and dedication by many people. Let’s meet some of the 17 strong recruitment team and find out their backgrounds, their views on recruitment and on working with IHS:

 

Continual Learning

At IHS we take personal development very seriously and are committed to providing all staff with the best possible platform for their future careers. As a matter of course the Company sponsors team members who wish to further their learning. Currently members of the recruitment, finance and HR teams are being supported to take Masters and Diploma courses in Business, Finance, IT, HR, Management and Organisational Change.

The Future

The next few years promise to be extremely exciting for the Company. An aggressive strategy of organic and acquisitive growth will provide real commercial challenges and opportunities. We are very keen to ensure that the next 5 years are as interesting and impressive as the first 5 years have been!

Why recruitment? Why IHS?

  • The environment is fast paced & the work challenging
  • There is a shared desire to succeed and to do the very best job possible for candidates and for clients
  • There is a continual commitment from the Company to develop the entire team & to reward achievers
  • A highly successful career can be forged within an organisation that is continuing to grow

 

www.i-hs.co.uk

Tags:

Features

Growing sales force gives Roche top marks.

by Admin 1. May 2006 05:00
With growth three times faster than the world market, a unique portfolio of products and an enviable pipeline, it’s no wonder Swiss healthcare company Roche has been voted “Employer of Choice 2005-2006.”*
Two sales representatives tell Pharmaceutical Field what makes Roche a truly outstanding organisation to work for.

Yvonne de Schoolmeester joined Roche earlier this year as an Oncology Hospital Sales specialist.

“Roche appealed to me due to its exciting portfolio of products and because it is one of the most respected pharmaceutical companies in the world.

“For me, it’s the combination of work ethics and company culture that makes Roche an excellent employer.

“Initially, I didn’t have to spend a long time from home on a course, as my training began online. It was a steep learning curve, but I received a lot of support which helped me to develop my product knowledge and gain a broader understanding of the industry.

“Now, I enjoy having the responsibility to manage my own business while knowing support is only a phone call away. I have regular contact with my line manager, who supports my business and career development, and a product trainer who helps to develop my knowledge and core skills.

“Working at Roche, I benefit from the support of a large organisation while also being part of a smaller, close-knit team and working independently. I meet with my colleagues to share knowledge and best practice, and together we can identify and overcome any hurdles so I don’t feel isolated.

“This support also helps me to work to my optimal capacity. I am able to see the right people, the right amount of times, to communicate the right messages ensuring a positive outcome from every meeting.

“Roche has a culture of open communication. I have honest and comfortable relationships with my colleagues and managers and am encouraged to ask questions and challenge decisions.

“The benefits package is excellent too. In addition to sales related bonus targets, there is the opportunity to reap rewards for innovative ideas, which heightens my motivation.

“Although my work can be challenging, it is very rewarding and I know that I am ultimately making a difference to patients’ lives, as they are receiving the treatments they deserve.”

Steve Brown has been a part of Roche since last August as a Medical Representative.

“I’d heard great things about Roche and was aware of its fantastic reputation among the public, industry and my peers.

“I was immediately struck by the company ethos. From the outset I was able to be forward-thinking and was given the opportunity to develop myself.

“My first few weeks at Roche were immensely enjoyable. Whilst hectic, I felt the initial training and introduction to the company was carried out at a good pace. There was a lot to learn about the product portfolio and therapy areas, while meeting a range of new people. Roche gave me confidence and trust, which meant I was more relaxed to get on with the job in hand.

“My role at Roche is diverse, and I encounter a different challenge every day. I meet a great variety of people from all walks of life, and I enjoy interacting with them on many levels.

“One of the hardest tasks I face is to motivate change among healthcare professionals – trying to get them to break old habits. I enjoy challenging current practice, and I get a real sense of achievement when a meeting goes well.

“It is, however, the invaluable behind-the-scenes work of head-office staff that enable me to excel at my job.

“As a leading pharmaceutical company, Roche has a number of initiatives which help create sales opportunities. In addition to helping me initiate dialogue with healthcare professionals, these also enhance my relationships.

“Roche also provides ongoing support, from my personal development plan including a variety of training courses, through to help with project management, which enables me to maximise my time with customers.

“While Roche is a large organisation, it’s the little things that make me feel a valued member of the company. Even though the managers are busy, I’m always impressed that they know my name and are very aware of the work/life balance, appreciating that I do have a family.

“To succeed, you need to be passionate about the role and, I’m motivated with the knowledge that I’m improving the quality of life for patients. Having the backing of a company like Roche gives me the opportunity to do this and enables me to perform to my best ability.”

Could Roche be right for you?

You must enjoy a challenge, be enthusiastic, committed and strong-minded. Along with good sales techniques, you need excellent interpersonal and networking skills so that you can quickly build relationships.

Roche now offers a direct in-house recruitment service and is actively seeking experienced sales people.

See full details of all vacancies at http://careers.roche.com/uk  and apply directly for a role or register in our talent pool.

You can also call us direct on  01707 366496  01707 366496 .

(*most desirable employer to work for as voted by readers of Pharmaceutical Field Magazine.)

Tags:

Features

TextBox

Tag cloud

Calendar

<<  May 2013  >>
MoTuWeThFrSaSu
293012345
6789101112
13141516171819
20212223242526
272829303112
3456789

View posts in large calendar